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Short answer
What is Thymosin Alpha 1?
Thymosin alpha-1 is a 28-amino-acid peptide, also called thymalfasin, identical to the natural human thymus peptide. MeSH classifies it as an immunologic adjuvant.
It also appears in the literature as Thymalfasin, Thymosin alpha 1, Talpha1.
Read the full explainer: what is Thymosin Alpha 1?What is in each Thymosin Alpha 1 vial?
| STRENGTH | FORM | PRICE | CERTIFICATE |
|---|---|---|---|
| 10mg | Lyophilised powder | A$118 | Pending |
What has research on Thymosin Alpha 1 examined?
Thymosin alpha-1 has been examined in cell and animal immunology studies and in human clinical trials, including randomized trials in chronic hepatitis B and studies as a vaccine adjuvant and in sepsis. Reviews summarise several decades of clinical investigation.
The table lists primary sources by year and model. Findings describe the study subjects, not this research vial.
| STUDY | YEAR | MODEL | PMID |
|---|---|---|---|
| Thymosin alpha 1: past clinical experience and future promise | 2010 | review | 20536460 |
| Historical review of thymosin α 1 in infectious diseases | 2015 | review | 26098768 |
| Thymosin alpha-1 | 2001 | review | 11381492 |
| The efficacy and safety of thymosin alpha-1 in Japanese patients with chronic hepatitis B; results from a randomized clinical trial | 2005 | human | 15850471 |
What adverse events have studies of Thymosin Alpha 1 reported?
In a phase 3 placebo-controlled trial in 1,106 adults with sepsis, no safety outcome differed significantly between groups (PMID 39814420). In a trial of 316 Japanese adults with chronic hepatitis B, all adverse drug reactions were mild, mostly liver-enzyme fluctuations (PMID 15850471). A 2026 Cochrane review rated the serious-adverse-event evidence low certainty (PMID 42713852).
These findings describe the people or animals in each study. The sources list gives every PubMed record.
How do you reconstitute and store Thymosin Alpha 1?
Store the sealed vial frozen (about -20 degrees Celsius), dry and away from light until it is reconstituted.
After reconstitution with a sterile solvent, keep the solution at 2 to 8 degrees Celsius and avoid repeated freezing and thawing. Record the solvent, volume and date on the vial label.
BAC Water is the usual laboratory solvent. Dilute acetic acid is an alternative for peptides that dissolve poorly in water. The reconstitution guide and storage guide cover laboratory handling.
| STATE | TEMPERATURE | NOTES |
|---|---|---|
| Sealed vial | -20 °C | Dry and dark. Keeps to the label date. |
| Reconstituted | 2 to 8 °C | Sterile technique. Avoid repeat freeze and thaw. |
| In transit | Cold pack | Refrigerate or freeze on arrival. |
Is Thymosin Alpha 1 legal to buy in Australia?
Thymosin Alpha 1 is not named in the Poisons Standard (June 2026 instrument). Source: the June 2026 Poisons Standard instrument (F2026L00633).
Thymosin Alpha 1 is not named on WADA's 2026 Prohibited List.
- POISONS STANDARD
- Not named
- WADA 2026
- Not named
- SALE TERMS
- Research use only
How fast does Thymosin Alpha 1 ship?
Orders placed before [cut-off] leave Western Australia the same business day with tracking, by [carrier]. Delivery estimates for each state are on the shipping page.
Thymosin Alpha 1 questions
What has research on thymosin alpha 1 examined?
Thymosin alpha-1 has been examined in cell and animal immunology studies and in human clinical trials, including randomized trials in chronic hepatitis B and studies as a vaccine adjuvant and in sepsis. Reviews summarise several decades of clinical investigation.
Is thymosin alpha 1 the same as TB500?
No. Thymosin alpha-1 is a 28-amino-acid peptide from the thymus. TB-500 is a 7-amino-acid fragment of thymosin beta-4, a structurally different protein. The shared name reflects where the peptides were first isolated.
Is thymosin alpha 1 a peptide?
Yes. Thymosin Alpha 1 is a peptide of 28 amino acids.
Is thymosin alpha 1 a prescription medicine in Australia?
Thymosin Alpha 1 is not named in the Poisons Standard (June 2026 instrument). Peptides Collective sells it for laboratory research use only.
Is thymosin alpha 1 banned in sport?
Thymosin Alpha 1 is not named on WADA's 2026 Prohibited List.
What is the CAS number for thymosin alpha 1?
The CAS number for Thymosin Alpha 1 is 62304-98-7. Its PubChem CID is 16130571.
How long does an unopened thymosin alpha 1 vial keep?
A sealed vial of lyophilised powder keeps to the date on its label when stored frozen, dry and dark. Once reconstituted, keep the solution at 2 to 8 degrees Celsius and record the date on the label.
Does every thymosin alpha 1 batch have a certificate?
Yes. Every Thymosin Alpha 1 batch is tested by [lab] before it goes on sale, and the certificate is published under the batch number printed on the vial. The current batch certificate is [pending].
Where is thymosin alpha 1 shipped from?
Orders ship tracked from Western Australia. Orders placed before [cut-off] leave the same business day. Delivery estimates by state are on the shipping page.
What purity is the current thymosin alpha 1 batch?
The current Thymosin Alpha 1 batch certificate is [pending]. When it is published, it reports purity by HPLC to three decimal places and confirms identity by mass spectrometry.
Which solvent reconstitutes thymosin alpha 1?
BAC Water (sterile water with 0.9% benzyl alcohol) is the usual laboratory solvent. Dilute acetic acid is an alternative for peptides that dissolve poorly in water. Record the solvent, volume and resulting concentration on the vial label.
How much does thymosin alpha 1 cost in Australia?
Thymosin Alpha 1 costs A$118 for 10mg at Peptides Collective, in Australian dollars. Each price is per vial of lyophilised powder.
Sources
- 1. Thymosin alpha 1: past clinical experience and future promise. Annals of the New York Academy of Sciences, 2010. PMID 20536460.
- 2. Historical review of thymosin α 1 in infectious diseases. Expert opinion on biological therapy, 2015. PMID 26098768.
- 3. Thymosin alpha-1. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2001. PMID 11381492.
- 4. The efficacy and safety of thymosin alpha-1 in Japanese patients with chronic hepatitis B; results from a randomized clinical trial. Journal of viral hepatitis, 2005. PMID 15850471.
- 5. The efficacy and safety of thymosin α1 for sepsis (TESTS): multicentre, double blinded, randomised, placebo controlled, phase 3 trial. 2025. PMID 39814420.
- 6. Thymosin-ɑ1 for people with chronic hepatitis B. 2026. PMID 42713852.
- 7. PubChem CID 16130571. National Library of Medicine.
- 8. Poisons Standard, June 2026 instrument (F2026L00633). Federal Register of Legislation.
- 9. World Anti-Doping Code, 2026 Prohibited List. WADA.
