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Short answer
What is ARA-290?
ARA-290, also called cibinetide, is an 11-amino-acid peptide derived from the helix B surface of erythropoietin. The literature describes it as a ligand of the innate repair receptor that does not stimulate red blood cell production.
It also appears in the literature as Cibinetide, ARA290, ARA 290, pHBSP, pyroglutamate helix B surface peptide.
What is in each ARA-290 vial?
| STRENGTH | FORM | PRICE | CERTIFICATE |
|---|---|---|---|
| 10mg | Lyophilised powder | A$85 | Pending |
What has research on ARA-290 examined?
Cibinetide has been examined in rodent models of neuropathic pain, ischaemia and inflammation. Small randomized, double-blind human trials have been published in sarcoidosis-associated small nerve fibre loss and in type 2 diabetes with neuropathy, plus a phase 2 study in diabetic macular oedema.
The table lists primary sources by year and model. Findings describe the study subjects, not this research vial.
What adverse events have studies of ARA-290 reported?
Two small placebo-controlled phase 2 trials reported no safety concerns or potential safety issues: 22 patients with sarcoidosis-associated small fiber neuropathy (intravenous, 4 weeks), and adults with type 2 diabetes and painful neuropathy (subcutaneous, 28 days) (PMID 23168581, 25387363). The abstracts list no specific adverse events.
These findings describe the people or animals in each study. The sources list gives every PubMed record.
How do you reconstitute and store ARA-290?
Store the sealed vial frozen (about -20 degrees Celsius), dry and away from light until it is reconstituted.
After reconstitution with a sterile solvent, keep the solution at 2 to 8 degrees Celsius and avoid repeated freezing and thawing. Record the solvent, volume and date on the vial label.
BAC Water is the usual laboratory solvent. Dilute acetic acid is an alternative for peptides that dissolve poorly in water. The reconstitution guide and storage guide cover laboratory handling.
| STATE | TEMPERATURE | NOTES |
|---|---|---|
| Sealed vial | -20 °C | Dry and dark. Keeps to the label date. |
| Reconstituted | 2 to 8 °C | Sterile technique. Avoid repeat freeze and thaw. |
| In transit | Cold pack | Refrigerate or freeze on arrival. |
Is ARA-290 legal to buy in Australia?
ARA-290 is not named in the Poisons Standard (June 2026 instrument). Source: the June 2026 Poisons Standard instrument (F2026L00633).
ARA-290 is not named on WADA's 2026 Prohibited List. WADA's S2.1.5 class covers innate repair receptor agonists, and the literature describes ARA-290 as one, so Sport Integrity Australia is the body to confirm its status.
- POISONS STANDARD
- Not named
- WADA 2026
- Not named
- SALE TERMS
- Research use only
How fast does ARA-290 ship?
Orders placed before [cut-off] leave Western Australia the same business day with tracking, by [carrier]. Delivery estimates for each state are on the shipping page.
ARA-290 questions
What has research on ARA-290 examined?
Cibinetide has been examined in rodent models of neuropathic pain, ischaemia and inflammation. Small randomized, double-blind human trials have been published in sarcoidosis-associated small nerve fibre loss and in type 2 diabetes with neuropathy, plus a phase 2 study in diabetic macular oedema.
Is ARA-290 peptide available in Australia?
Yes. Peptides Collective sells ARA-290 in Australia for laboratory research use only, at A$85 for 10mg, with a certificate for every batch. ARA-290 is not named in the Poisons Standard (June 2026 instrument).
What are the differences between ARA-290 peptide and BPC-157?
ARA-290 is an 11-amino-acid peptide derived from erythropoietin and studied as an innate repair receptor ligand, including in small controlled human trials. BPC-157 is a 15-amino-acid peptide from a gastric protein, studied mainly in rodents. BPC-157 is Schedule 4 in Australia; ARA-290 is not named in the Poisons Standard.
Is ARA-290 a prescription medicine in Australia?
ARA-290 is not named in the Poisons Standard (June 2026 instrument). Peptides Collective sells it for laboratory research use only.
Is ARA-290 banned in sport?
ARA-290 is not named on WADA's 2026 Prohibited List. WADA's S2.1.5 class covers innate repair receptor agonists, and the literature describes ARA-290 as one, so Sport Integrity Australia is the body to confirm its status.
What is the CAS number for ARA-290?
The CAS number for ARA-290 is 1208243-50-8. Its PubChem CID is 91810664.
How long does an unopened ARA-290 vial keep?
A sealed vial of lyophilised powder keeps to the date on its label when stored frozen, dry and dark. Once reconstituted, keep the solution at 2 to 8 degrees Celsius and record the date on the label.
Does every ARA-290 batch have a certificate?
Yes. Every ARA-290 batch is tested by [lab] before it goes on sale, and the certificate is published under the batch number printed on the vial. The current batch certificate is [pending].
Where is ARA-290 shipped from?
Orders ship tracked from Western Australia. Orders placed before [cut-off] leave the same business day. Delivery estimates by state are on the shipping page.
What purity is the current ARA-290 batch?
The current ARA-290 batch certificate is [pending]. When it is published, it reports purity by HPLC to three decimal places and confirms identity by mass spectrometry.
Which solvent reconstitutes ARA-290?
BAC Water (sterile water with 0.9% benzyl alcohol) is the usual laboratory solvent. Dilute acetic acid is an alternative for peptides that dissolve poorly in water. Record the solvent, volume and resulting concentration on the vial label.
How much does ARA-290 cost in Australia?
ARA-290 costs A$85 for 10mg at Peptides Collective, in Australian dollars. Each price is per vial of lyophilised powder.
Sources
- 1. Safety and efficacy of ARA 290 in sarcoidosis patients with symptoms of small fiber neuropathy: a randomized, double-blind pilot study. Molecular medicine (Cambridge, Mass.), 2012. PMID 23168581.
- 2. ARA 290 improves symptoms in patients with sarcoidosis-associated small nerve fiber loss and increases corneal nerve fiber density. Molecular medicine (Cambridge, Mass.), 2013. PMID 24136731.
- 3. ARA 290, a nonerythropoietic peptide engineered from erythropoietin, improves metabolic control and neuropathic symptoms in patients with type 2 diabetes. Molecular medicine (Cambridge, Mass.), 2015. PMID 25387363.
- 4. ARA 290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain coupled with suppression of the spinal microglia response. Molecular pain, 2014. PMID 24529189.
- 5. ARA 290 for treatment of small fiber neuropathy in sarcoidosis. Expert opinion on investigational drugs, 2014. PMID 24555851.
- 6. PubChem CID 91810664. National Library of Medicine.
- 7. Poisons Standard, June 2026 instrument (F2026L00633). Federal Register of Legislation.
- 8. World Anti-Doping Code, 2026 Prohibited List. WADA.
