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Short answer
What is Epithalon?
Epithalon (also spelled epitalon) is a synthetic tetrapeptide, Ala-Glu-Asp-Gly, modelled on a pineal gland extract called epithalamin.
It also appears in the literature as Epitalon, Epithalon, Epithalone, Ala-Glu-Asp-Gly, AEDG.
What is in each Epithalon vial?
| STRENGTH | FORM | PRICE | CERTIFICATE |
|---|---|---|---|
| 10mg | Lyophilised powder | A$53 | Pending |
What has research on Epithalon examined?
Research on Epitalon is mainly cell-culture work (including telomerase and telomere-length studies in human cell lines) and animal studies, mostly from one research group. Human reports mainly concern the related pineal extract epithalamin, and few concern the synthetic tetrapeptide; large independent controlled trials were not found.
The table lists primary sources by year and model. Findings describe the study subjects, not this research vial.
| STUDY | YEAR | MODEL | PMID |
|---|---|---|---|
| Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells | 2003 | cell | 12937682 |
| Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity | 2025 | cell | 40908429 |
| Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties | 2025 | review | 40141333 |
| Peptides of pineal gland and thymus prolong human life | 2003 | human | 14523363 |
What adverse events have studies of Epithalon reported?
We found no human study of synthetic Epitalon that reports adverse events. In mouse studies involving the developers' group, the authors report no toxic effect from long-term low-dose injections (PMID 16634527), and no change in food intake, body weight, mean lifespan or total spontaneous tumour incidence (PMID 14501183).
These findings describe the people or animals in each study. The sources list gives every PubMed record.
How do you reconstitute and store Epithalon?
Store the sealed vial frozen (about -20 degrees Celsius), dry and away from light until it is reconstituted.
After reconstitution with a sterile solvent, keep the solution at 2 to 8 degrees Celsius and avoid repeated freezing and thawing. Record the solvent, volume and date on the vial label.
BAC Water is the usual laboratory solvent. Dilute acetic acid is an alternative for peptides that dissolve poorly in water. The reconstitution guide and storage guide cover laboratory handling.
| STATE | TEMPERATURE | NOTES |
|---|---|---|
| Sealed vial | -20 °C | Dry and dark. Keeps to the label date. |
| Reconstituted | 2 to 8 °C | Sterile technique. Avoid repeat freeze and thaw. |
| In transit | Cold pack | Refrigerate or freeze on arrival. |
Is Epithalon legal to buy in Australia?
Epithalon is not named in the Poisons Standard (June 2026 instrument). Source: the June 2026 Poisons Standard instrument (F2026L00633).
Epithalon is not named on WADA's 2026 Prohibited List. WADA's S0 class covers any substance without government approval for human use, so Sport Integrity Australia is the body to confirm its status.
- POISONS STANDARD
- Not named
- WADA 2026
- Not named
- SALE TERMS
- Research use only
How fast does Epithalon ship?
Orders placed before [cut-off] leave Western Australia the same business day with tracking, by [carrier]. Delivery estimates for each state are on the shipping page.
Epithalon questions
What has research on epithalon examined?
Research on Epitalon is mainly cell-culture work (including telomerase and telomere-length studies in human cell lines) and animal studies, mostly from one research group. Human reports mainly concern the related pineal extract epithalamin, and few concern the synthetic tetrapeptide; large independent controlled trials were not found.
Is Epitalon legal in Australia?
Epithalon is not named in the Poisons Standard (June 2026 instrument). Peptides Collective sells it for laboratory research use only.
What adverse events have studies of epithalon reported?
We found no human study of synthetic Epitalon that reports adverse events. In mouse studies involving the developers' group, the authors report no toxic effect from long-term low-dose injections (PMID 16634527), and no change in food intake, body weight, mean lifespan or total spontaneous tumour incidence (PMID 14501183).
Is epithalon a peptide?
Yes. Epithalon is a peptide of 4 amino acids.
Is epithalon a prescription medicine in Australia?
Epithalon is not named in the Poisons Standard (June 2026 instrument). Peptides Collective sells it for laboratory research use only.
Is epithalon banned in sport?
Epithalon is not named on WADA's 2026 Prohibited List. WADA's S0 class covers any substance without government approval for human use, so Sport Integrity Australia is the body to confirm its status.
What is the CAS number for epithalon?
The CAS number for Epithalon is 307297-39-8. Its PubChem CID is 219042.
How long does an unopened epithalon vial keep?
A sealed vial of lyophilised powder keeps to the date on its label when stored frozen, dry and dark. Once reconstituted, keep the solution at 2 to 8 degrees Celsius and record the date on the label.
Does every epithalon batch have a certificate?
Yes. Every Epithalon batch is tested by [lab] before it goes on sale, and the certificate is published under the batch number printed on the vial. The current batch certificate is [pending].
Where is epithalon shipped from?
Orders ship tracked from Western Australia. Orders placed before [cut-off] leave the same business day. Delivery estimates by state are on the shipping page.
What purity is the current epithalon batch?
The current Epithalon batch certificate is [pending]. When it is published, it reports purity by HPLC to three decimal places and confirms identity by mass spectrometry.
Which solvent reconstitutes epithalon?
BAC Water (sterile water with 0.9% benzyl alcohol) is the usual laboratory solvent. Dilute acetic acid is an alternative for peptides that dissolve poorly in water. Record the solvent, volume and resulting concentration on the vial label.
Sources
- 1. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bulletin of experimental biology and medicine, 2003. PMID 12937682.
- 2. Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity. Biogerontology, 2025. PMID 40908429.
- 3. Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties. International journal of molecular sciences, 2025. PMID 40141333.
- 4. Peptides of pineal gland and thymus prolong human life. Neuro endocrinology letters, 2003. PMID 14523363.
- 5. Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He mice. 2006. PMID 16634527.
- 6. Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. 2003. PMID 14501183.
- 7. PubChem CID 219042. National Library of Medicine.
- 8. Poisons Standard, June 2026 instrument (F2026L00633). Federal Register of Legislation.
- 9. World Anti-Doping Code, 2026 Prohibited List. WADA.
