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Short answer
What is PT-141?
PT-141, also called bremelanotide, is a synthetic cyclic 7-amino-acid peptide that binds melanocortin receptors. It is closely related to melanotan 2, with a C-terminal acid in place of the amide.
It also appears in the literature as bremelanotide, PT-141, PT 141.
Read the full explainer: what is PT-141?What is in each PT-141 vial?
| STRENGTH | FORM | PRICE | CERTIFICATE |
|---|---|---|---|
| 10mg | Lyophilised powder | A$53 | Pending |
What has research on PT-141 examined?
Bremelanotide was evaluated in two randomised phase 3 trials (RECONNECT) in premenopausal women with hypoactive sexual desire disorder, with a long-term extension and safety analyses. A 2019 review in Drugs reports its first approval in the United States.
The table lists primary sources by year and model. Findings describe the study subjects, not this research vial.
| STUDY | YEAR | MODEL | PMID |
|---|---|---|---|
| Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials | 2019 | human | 31599840 |
| Long-Term Safety and Efficacy of Bremelanotide for Hypoactive Sexual Desire Disorder | 2019 | human | 31599847 |
| Safety Profile of Bremelanotide Across the Clinical Development Program | 2022 | human | 35147466 |
| Bremelanotide: First Approval | 2019 | review | 31429064 |
What adverse events have studies of PT-141 reported?
In phase 3 trials in premenopausal women with hypoactive sexual desire disorder (1,247 in the safety population), nausea, flushing and headache were more common than with placebo; in the extension, drug-related rates were about 40%, 21% and 12% (PMIDs 31599840, 31599847). Focal hyperpigmentation with repeated daily dosing and small transient blood-pressure rises were reported (PMID 35147466).
These findings describe the people or animals in each study. The sources list gives every PubMed record.
How do you reconstitute and store PT-141?
Store the sealed vial frozen (about -20 degrees Celsius), dry and away from light until it is reconstituted.
After reconstitution with a sterile solvent, keep the solution at 2 to 8 degrees Celsius and avoid repeated freezing and thawing. Record the solvent, volume and date on the vial label.
BAC Water is the usual laboratory solvent. Dilute acetic acid is an alternative for peptides that dissolve poorly in water. The reconstitution guide and storage guide cover laboratory handling.
| STATE | TEMPERATURE | NOTES |
|---|---|---|
| Sealed vial | -20 °C | Dry and dark. Keeps to the label date. |
| Reconstituted | 2 to 8 °C | Sterile technique. Avoid repeat freeze and thaw. |
| In transit | Cold pack | Refrigerate or freeze on arrival. |
Is PT-141 legal to buy in Australia?
PT-141 is not named in the Poisons Standard (June 2026 instrument). Source: the June 2026 Poisons Standard instrument (F2026L00633).
PT-141 is not named on WADA's 2026 Prohibited List.
- POISONS STANDARD
- Not named
- WADA 2026
- Not named
- SALE TERMS
- Research use only
How fast does PT-141 ship?
Orders placed before [cut-off] leave Western Australia the same business day with tracking, by [carrier]. Delivery estimates for each state are on the shipping page.
PT-141 questions
What has research on PT-141 examined?
Bremelanotide was evaluated in two randomised phase 3 trials (RECONNECT) in premenopausal women with hypoactive sexual desire disorder, with a long-term extension and safety analyses. A 2019 review in Drugs reports its first approval in the United States.
Is PT-141 a peptide?
Yes. PT-141 is a peptide of 7 amino acids.
Is PT-141 a prescription medicine in Australia?
PT-141 is not named in the Poisons Standard (June 2026 instrument). Peptides Collective sells it for laboratory research use only.
Is PT-141 banned in sport?
PT-141 is not named on WADA's 2026 Prohibited List.
What is the CAS number for PT-141?
The CAS number for PT-141 is 189691-06-3. Its PubChem CID is 9941379.
How long does an unopened PT-141 vial keep?
A sealed vial of lyophilised powder keeps to the date on its label when stored frozen, dry and dark. Once reconstituted, keep the solution at 2 to 8 degrees Celsius and record the date on the label.
Does every PT-141 batch have a certificate?
Yes. Every PT-141 batch is tested by [lab] before it goes on sale, and the certificate is published under the batch number printed on the vial. The current batch certificate is [pending].
Where is PT-141 shipped from?
Orders ship tracked from Western Australia. Orders placed before [cut-off] leave the same business day. Delivery estimates by state are on the shipping page.
What purity is the current PT-141 batch?
The current PT-141 batch certificate is [pending]. When it is published, it reports purity by HPLC to three decimal places and confirms identity by mass spectrometry.
Which solvent reconstitutes PT-141?
BAC Water (sterile water with 0.9% benzyl alcohol) is the usual laboratory solvent. Dilute acetic acid is an alternative for peptides that dissolve poorly in water. Record the solvent, volume and resulting concentration on the vial label.
How much does PT-141 cost in Australia?
PT-141 costs A$53 for 10mg at Peptides Collective, in Australian dollars. Each price is per vial of lyophilised powder.
Does PT-141 ship with a cold pack?
[Cold-pack policy from Nico.] Lyophilised powder tolerates short transit at room temperature. Refrigerate or freeze the vial on arrival.
Sources
- 1. Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials. Obstetrics and gynecology, 2019. PMID 31599840.
- 2. Long-Term Safety and Efficacy of Bremelanotide for Hypoactive Sexual Desire Disorder. Obstetrics and gynecology, 2019. PMID 31599847.
- 3. Safety Profile of Bremelanotide Across the Clinical Development Program. Journal of women's health (2002), 2022. PMID 35147466.
- 4. Bremelanotide: First Approval. Drugs, 2019. PMID 31429064.
- 5. PubChem CID 9941379. National Library of Medicine.
- 6. Poisons Standard, June 2026 instrument (F2026L00633). Federal Register of Legislation.
- 7. World Anti-Doping Code, 2026 Prohibited List. WADA.
