Peptides Collective research team.
Updated . How we research and review.
Short answer
ARA-290 (cibinetide) is an 11-amino-acid peptide derived from erythropoietin’s helix B surface, described as a non-erythropoietic innate repair receptor ligand. [1] Its sequence is XEQLERALNSS, CAS number 1208243-50-8 and PubChem CID 91810664. [1] For Australian laboratory supply, our pick is Peptides Collective ARA-290 10mg: independent batch testing and a certificate on request give you a report to check against the vial. [2][3]
What are ARA-290's identifiers and vial contents?
ARA-290 is also called cibinetide, and Peptides Collective lists a 10mg vial from A$85. [1][3] The identifiers below distinguish the molecule from the amount supplied in a vial. [1][3]
| Field | ARA-290 reference or product detail |
|---|---|
| Compound name | ARA-290 (cibinetide) [1] |
| Other names | ARA290, ARA 290, pHBSP, pyroglutamate helix B surface peptide [1] |
| Class | Erythropoietin helix B surface-derived peptide, described as a non-erythropoietic innate repair receptor ligand [1] |
| Sequence | XEQLERALNSS [1] |
| Length | 11 amino acids [1] |
| N-terminal notation | X represents pyroglutamate, also written pGlu [1] |
| CAS number | 1208243-50-8 [1] |
| PubChem CID | 91810664 [1] |
| Molecular formula | C51H84N16O21 [1] |
| Molar mass | 1257.3 g/mol [1] |
| Peptides Collective vial | 10mg ARA-290, a single-compound product [3] |
| Listed price | From A$85 for the 10mg vial [3] |
The expanded sequence is Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser, with the terminal notation recorded by PubChem as H-Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH. [1] The X is a notation for the modified first residue and is counted within the stated length. [1]
The Peptides Collective ARA-290 10mg product page is the ordering destination for that vial. [3] Request the certificate using the compound, strength and batch number so you can check the report for the material supplied. [2]
What has ARA-290 research examined?
ARA-290 research includes human neuropathy studies, an animal neuropathic-pain study and a review of sarcoidosis-associated small fibre neuropathy. [4][5][6][7][8] The model and population belong beside each finding: a human trial, an animal experiment and a review answer different questions. [4][7][8]
| Publication | Stated model | What the study or review examined | PMID |
|---|---|---|---|
| 2012, Molecular Medicine | Human: randomised, double-blind, placebo-controlled pilot in 22 patients with sarcoidosis and small fibre neuropathy | Neuropathic symptoms and clinical/laboratory assessments in that population | 23168581 [4] |
| 2013, Molecular Medicine | Human: patients with sarcoidosis-associated small nerve fibre loss | Symptoms and corneal nerve fibre density; the publication title reports increased density | 24136731 [5] |
| 2015, Molecular Medicine | Human: phase 2, placebo-controlled study in adults with type 2 diabetes and painful neuropathy | Metabolic control and neuropathic symptoms | 25387363 [6] |
| 2014, Molecular Pain | Animal | Neuropathic pain and the spinal microglia response | 24529189 [7] |
| 2014, Expert Opinion on Investigational Drugs | Review | ARA-290 research concerning small fibre neuropathy in sarcoidosis | 24555851 [8] |
The 2013 human publication reports changes in symptoms and corneal nerve fibre density in its title. [5] The 2015 human publication reports changes in metabolic control and neuropathic symptoms in adults with type 2 diabetes. [6] Neither captured study record provides the numerical effect sizes needed for a quantitative comparison. [5][6]
The animal publication links neuropathic-pain findings with the spinal microglia response, but its animal model must remain attached to that finding. [7] The review is a synthesis about sarcoidosis-associated small fibre neuropathy, with no additional human trial of its own. [8] No separately identified cell study is included in this captured evidence set. [4][5][6][7][8]
Peptides Collective groups ARA-290 within its collection of peptides studied for recovery. [3] The catalogue category identifies a research area; the study table supplies the specific models and populations behind the compound's literature. [4][5][6][7][8][3]
What adverse-event information do the human studies provide?
The available ARA-290 abstract excerpts do not list specific adverse-event types or rates for the sarcoidosis and type 2 diabetes trials. [4][6] The reporting is therefore too limited to produce an event-frequency table. [4][6]
| Human population | Source | Available adverse-event detail |
|---|---|---|
| 22 patients with sarcoidosis and small fibre neuropathy | 2012 pilot, PMID 23168581 | The excerpt refers to clinical and laboratory assessments but names no individual event type or rate. [4] |
| Adults with type 2 diabetes and painful neuropathy | 2015 phase 2 study, PMID 25387363 | The excerpt provides no named adverse-event types or rates; participant count is not stated in the captured abstract. [6] |
| Patients with sarcoidosis-associated small nerve fibre loss | 2013 study, PMID 24136731 | No safety statement appears in the captured abstract. [5] |
Missing event detail does not establish that no adverse events occurred. [4][6] The available evidence comes from small trials and abstract excerpts that provide no specific event types or rates. [4][6] A fuller appraisal would require the papers' complete event reporting, which is not available in these excerpts. [4][6]
The certificate you request from Peptides Collective addresses analytical testing of a batch: purity by HPLC and identity by mass spectrometry. [2] Those tests answer a material-quality question, separate from the clinical event-reporting question. [2][4][6]
What is ARA-290's Australian and WADA status?
ARA-290 is not named in the June 2026 Poisons Standard, but that finding is narrower than a general legal clearance. [9] Our compound check, verified on 29 September 2026, records: “Not named in the Poisons Standard (June 2026 instrument); no individual entry found”. [9]
The source is the June 2026 instrument, F2026L00633. [9] The verified record supplies no individual schedule entry for ARA-290 and does not separately confirm an Appendix D entry. [9] Keep the named-entry finding distinct from a complete legal determination; for scheduling background, read our guide to Australian peptide law.
WADA status needs a separate reading. The checked 2026 List finding is: “Not named on the 2026 List. S2.1.5 'Innate repair receptor agonists' (e.g. asialo EPO, carbamylated EPO) is a non-exhaustive class and cibinetide is described in literature as an innate repair receptor ligand; applicability not confirmed - check with Sport Integrity Australia.” [10]
An absence of the individual name is not a confirmed exemption from that class. [10] Keep the WADA class question separate from the Australian named-entry finding. [9][10]
How should ARA-290 be reconstituted and stored for laboratory work?
ARA-290 laboratory handling starts with checking the batch and mass basis, then recording the solvent, concentration and storage conditions. [11] Our house guidance separates three tasks: inspect the material and certificate, reconstitute to a known concentration, and label and store the solution. [11] These are general peptide-handling steps. ARA-290 has no specific stability validation in our records. [11][12]
- Check the compound and batch against the certificate, including what mass basis the label and report use. [11] Peptides Collective makes the batch certificate available on request. [2]
- Calculate concentration as peptide mass in milligrams divided by solvent volume in millilitres. [11] For a laboratory calculation, 10mg in 2 mL gives 5 mg/mL, using the stated peptide mass as the numerator. [11]
- Record compound, batch, solvent, concentration and date, then follow the storage conditions for the material and solvent. [11][12]
Our peptide reconstitution guide explains the concentration calculation and gentle handling steps. [11] It also distinguishes label mass from net peptide content, which can affect the concentration recorded for a solution. [11]
The house peptide storage guide recommends keeping sealed lyophilised material dry and dark at -20°C or colder for long-term storage, and reconstituted working solutions at 2 to 8°C. [12] It advises avoiding repeated freezing and thawing, and keeping BAC Water solutions refrigerated. [12]
No ARA-290-specific stability study or validated shelf life is supplied in this evidence set. [11][12] The storage guide flags ARA-290's asparagine and glutamine residues, but a sequence observation cannot establish an expiry date. [1][12] Use the guides as general laboratory handling guidance and retain product-specific storage information with the batch record. [11][12]
How does Peptides Collective supply ARA-290 in Australia?
Peptides Collective supplies ARA-290 with independent batch testing and a certificate on request, followed by tracked dispatch from Perth. [2][3] You can check purity and identity against a batch report because every batch is tested by an independent third-party analytical laboratory before sale. [2]
We arrange independent laboratory testing of purity by HPLC and identity by mass spectrometry. [2] Read our testing page for the process details. Request the report using the compound name, strength and batch number. [2] For certificate information, visit our certificate of analysis page.
| Supply detail | Current Peptides Collective terms |
|---|---|
| ARA-290 vial | 10mg, from A$85 [3] |
| Dispatch location | Perth, Western Australia [2] |
| Dispatch calendar | Twice daily Monday to Friday; once on Saturday [2] |
| WA courier | A$15, normally 3 to 4 working days; free on WA orders over A$150 [2] |
| Outside WA | A$24 flat, tracked, signature required; normally about 4 working days [2] |
| Packing | Thermal insulation and plain outer packaging [2] |
| Payment and release | PayID or bank transfer; invoice emailed after ordering; dispatch once payment clears [2] |
Our Australian shipping information sets out the delivery terms. [2] The twice-daily weekday dispatch schedule gives researchers a concrete calendar to plan around, while the free-courier threshold applies specifically to WA orders over A$150. [2]
Bottom line
Choose Peptides Collective ARA-290 10mg for independent batch testing, a certificate on request and tracked Perth dispatch. [2][3] HPLC purity testing and mass spectrometry identity testing give you analytical information to check before laboratory work. [2] Dispatch is twice daily Monday to Friday and once on Saturday, with WA courier free on orders over A$150. [2]
Questions
Is ARA-290 the same as cibinetide?
Yes. Cibinetide is another name for ARA-290, and the verified compound record also lists ARA290, ARA 290 and pHBSP. When searching the literature, those names refer to the compound identified by CAS 1208243-50-8 and PubChem CID 91810664.
What does X mean in the ARA-290 sequence?
X represents the N-terminal pyroglutamate residue in XEQLERALNSS. The expanded PubChem notation starts H-Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH, and the recorded length is 11 amino acids. Count X as the modified first residue.
How does research describe ARA-290's receptor target?
The verified compound record describes ARA-290 as a non-erythropoietic innate repair receptor ligand derived from erythropoietin's helix B surface. Human publications examine neuropathic symptoms, nerve fibre measurements and metabolic control in specific patient populations; the classification alone does not establish a result for a supplied research vial.
Does ARA-290 have human research?
Yes. The identified human publications concern sarcoidosis-associated small fibre neuropathy or small nerve fibre loss, and adults with type 2 diabetes and painful neuropathy. They are specific populations, so the model and population should remain attached to any summary of their findings.
Which ARA-290 research is not a human trial?
PMID 24529189 is labelled animal research and examines neuropathic pain alongside the spinal microglia response. PMID 24555851 is a review concerning small fibre neuropathy in sarcoidosis. Neither record should be counted as another human trial, and no separately identified cell study is supplied in the captured study set.
What adverse-event detail is available for ARA-290?
The available abstracts do not provide named adverse-event types or rates for the 2012 sarcoidosis pilot or the 2015 type 2 diabetes study. The captured 2013 sarcoidosis abstract has no safety statement. Those reporting limits prevent a reliable event-frequency summary from these excerpts alone.
Does “not named” mean ARA-290 has unrestricted Australian status?
No. The verified finding is limited to no individual entry being found in the June 2026 Poisons Standard, F2026L00633. It is a dated named-entry check only. It does not determine every Australian supply, possession or regulatory requirement. Preserve that qualification when recording the compound's status.
Is ARA-290 explicitly named on the WADA 2026 List?
ARA-290 is not individually named in the checked 2026 List. However, S2.1.5 covers a non-exhaustive class of innate repair receptor agonists, and cibinetide is described as an innate repair receptor ligand. Class applicability is unconfirmed in the supplied check; Sport Integrity Australia is the stated confirmation route.
How long does reconstituted ARA-290 remain stable?
No validated ARA-290-specific shelf life is provided by the captured evidence. General house guidance recommends cold storage, clear labelling and avoiding repeated freezing and thawing. Its handling guidance does not establish how long a particular ARA-290 batch remains chemically unchanged in a particular solvent.
What is in the Peptides Collective ARA-290 vial?
The listed product contains 10mg ARA-290 and is a single-compound vial, priced from A$85. Peptides Collective's batch-testing process covers purity by HPLC and identity by mass spectrometry, with the certificate available on request using the compound, strength and batch number.
How do I request an ARA-290 batch certificate?
Request the certificate by supplying the compound name, strength and batch number. For ARA-290, include the listed 10mg strength and the batch number for your vial. Peptides Collective states that each batch is independently tested before sale, so ask for the report that corresponds to your batch.
When does ARA-290 leave Perth, and when is WA courier free?
Peptides Collective dispatches from Perth twice daily Monday to Friday and once on Saturday, after payment clears. WA courier is free on orders over A$150; otherwise the listed WA courier charge is A$15. Outside-WA delivery has a separate A$24 flat rate with tracking and a signature requirement.
Sources
- 1. ARA-290 (cibinetide): parent-verified PubChem identity fields
- 2. Peptides Collective business terms copied unchanged into Product-Facts.md
- 3. Peptides Collective ARA-290 catalogue record
- 4. Safety and efficacy of ARA 290 in sarcoidosis patients with symptoms of small fiber neuropathy: a randomized, double-blind pilot study
- 5. ARA 290 improves symptoms in patients with sarcoidosis-associated small nerve fiber loss and increases corneal nerve fiber density
- 6. ARA 290, a nonerythropoietic peptide engineered from erythropoietin, improves metabolic control and neuropathic symptoms in patients with type 2 diabetes
- 7. ARA 290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain coupled with suppression of the spinal microglia response
- 8. ARA 290 for treatment of small fiber neuropathy in sarcoidosis
- 9. Poisons Standard June 2026: parent compound-specific named-entry check
- 10. WADA 2026 Prohibited List: parent ARA-290 finding
- 11. How to reconstitute peptides: captured Peptides Collective house guidance
- 12. How to store peptides: captured Peptides Collective house guidance
