Peptides Collective research team.
Updated . How we research and review.
Short answer
KPV is the tripeptide Lys-Pro-Val, a three-amino-acid fragment of alpha-melanocyte-stimulating hormone, with CAS 67727-97-3 and PubChem CID 125672. [1] The dated research check found cell and mouse studies but no human KPV clinical trial. [2][3][4] For Australian laboratory procurement, our pick is the Peptides Collective KPV vial because each batch is independently tested before sale. [5]
What identifies KPV and what is in our vial?
KPV is the Lys-Pro-Val tripeptide, and Peptides Collective supplies it as a single-compound vial with listed content of 10mg. [1][9] Match the chemical identifiers as well as the product name when checking a research record. [1]
| Identifier or product detail | Recorded value |
|---|---|
| Compound class | Tripeptide matching the C-terminal residues 11-13 of alpha-MSH [1] |
| Sequence | Lys-Pro-Val; one-letter sequence KPV [1] |
| Length | 3 amino acids [1] |
| CAS | 67727-97-3 [1] |
| PubChem CID | 125672 [1] |
| Molecular formula | C16H30N4O4 [1] |
| Molar mass | 342.43 g/mol [1] |
| Other recorded names | L-Lysyl-L-prolyl-L-valine; alpha-MSH (11-13) [1] |
| Peptides Collective vial | KPV, listed content 10mg [9] |
A name-only search needs care: the verified PubChem check found that searching “KPV” can resolve to an unrelated compound, while CID 125672 identifies Lys-Pro-Val. [1] Use that CID alongside the CAS when comparing records. [1]
The vial's listed content and a batch's measured analytical results are separate pieces of information. [9][10] HPLC purity and net peptide content are also distinct, so the catalogue's 10mg figure is a label specification. The batch content measurement is on the certificate, available on request. [9][10]
What has KPV research examined?
KPV research in the verified records examines cell signalling and intestinal inflammation in mouse models, alongside a review of alpha-MSH-related peptides. [2][6][3][7] The model label matters: these records do not establish a clinical result in people. [4]
| Model | Study and PMID | Research focus |
|---|---|---|
| Animal | 2008, Gastroenterology, PMID 18061177 | PepT1-mediated KPV uptake and intestinal inflammation [2] |
| Animal | 2008, Inflammatory Bowel Diseases, PMID 18092346 | Melanocortin-derived KPV in murine models of inflammatory bowel disease [6] |
| Cell | 2004, The Journal of Investigative Dermatology, PMID 15102092 | Alpha-MSH, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cells [3] |
| Review | 2010, Advances in Experimental Medicine and Biology, PMID 21222263 | Alpha-MSH-related peptides and inflammatory effects beyond the pharmacophore [7] |
| Human | No human KPV clinical trial identified in the dated PubMed check | No captured human trial to summarise [4] |
The keratinocyte paper uses human cells, but its stated model is cell culture. [3] Keep it in the cell category when assessing the evidence. [3]
The supplied research summary also describes intestinal epithelial cell work and mouse colitis studies using delivery systems such as nanoparticles or hydrogels. [2] Those experimental settings are part of the research context; they do not establish a result for a catalogue vial. [2][9]
What adverse events have KPV studies reported?
The PubMed check dated 29 September 2026 found no KPV study reporting adverse events, and the fetched cell and rodent-colitis abstracts do not report them. [4] No human KPV study was identified in that check. [4]
There is therefore no attributable human population, participant count or adverse-event rate to report from these records. [4] For the animal evidence, the search summary specifically notes that the mouse-study abstract for PMID 18092346 reports efficacy only. [4]
An absence of adverse-event reporting does not establish that no events occurred. [4] The available abstracts provide no attributable list of reactions or their incidence. [4]
What is KPV's Australian legal and WADA status?
KPV is not named in the Poisons Standard, June 2026 instrument F2026L00633; the compound check dated 29 September 2026 found no individual entry. [11] No KPV-specific Appendix D listing is identified in that check. [11]
That finding is the supported Australian scheduling statement only. It grants no permission or approval. [11] The distinctions between compound entries are covered in our guide to Australian peptide law. [11]
The separate WADA check records the following status verbatim: Not named on the 2026 List. Class S0 (Non-approved substances) prohibits at all times any pharmacological substance not addressed elsewhere and with no current governmental approval for human therapeutic use; whether S0 applies was not confirmed here - check with Sport Integrity Australia. [12]
KPV's absence by name does not settle whether the S0 class applies. [12] Australian scheduling and sport eligibility are separate questions, and neither check should be substituted for the other. [11][12]
How should KPV be reconstituted and stored for laboratory research?
Reconstitute KPV to a recorded laboratory concentration, then choose storage according to the material's physical form and solvent. [10][13] The available handling guidance is general peptide guidance. No KPV-specific solubility or stability study was found. [10][13]
For lyophilised material, reconstitution dissolves the peptide in a sterile solvent to a known concentration. [10] The calculation is peptide mass in milligrams divided by solvent volume in millilitres: the captured example of 10mg in 2 mL gives a nominal concentration of 5 mg/mL. [10] It is an arithmetic example only. No solvent is validated for KPV. [10]
Check whether the mass figure represents net peptide content or total powder before relying on the calculation. [10] Use the Peptides Collective laboratory reconstitution guide to check that distinction and the concentration maths. [10]
For storage, the house guidance distinguishes the dry material from a solution. [13]
| Material or solvent | General house guidance |
|---|---|
| Sealed lyophilised peptide | Keep dry and dark at -20°C or colder for long-term storage; 2 to 8°C for short-term keeping [13] |
| Reconstituted working solution | Keep at 2 to 8°C; label compound, batch number, solvent, concentration and date of first puncture [13] |
| Solution containing BAC Water | Keep refrigerated under the house guide's solvent-specific rule; its freezer precaution is based on antibody evidence; no KPV study was found [13] |
The peptide storage guide covers the solvent-dependent freezing guidance and the limits of general shelf-life advice. [13] Neither captured handling guide supplies a measured shelf life for reconstituted KPV. [10][13]
Why order KPV from Peptides Collective?
Peptides Collective is our pick for KPV procurement because you can request a batch certificate and order from Perth-held stock with a stated dispatch schedule. [5][8] You get a defined testing process and a local dispatch schedule for your order. [5][8]
Our KPV vial is batch tested by an independent lab before sale: purity by HPLC and identity by mass spectrometry. [5] Our testing process sets out those analytical checks. [5]
You can obtain the certificate on request by supplying the compound, strength and batch number. [5] Use our certificate information as the starting point for that request. [5]
We dispatch from Perth, Western Australia, twice daily Monday to Friday and once on Saturday, after payment clears. [8] WA courier is A$15 and free on WA orders over A$150, with normal delivery in 3 to 4 working days. [8] Orders go out in thermal insulation and plain outer packaging. [8] Check the dispatch and delivery details when planning your order. [8]
Bottom line
Choose the Peptides Collective KPV 10mg vial for independent batch testing, a certificate on request and fast tracked dispatch from Perth. [9][5][8] The dispatch schedule is twice daily Monday to Friday and once on Saturday, with WA courier free on WA orders over A$150. [8] Keep the research conclusion separate: the verified studies are cell and animal work plus a review, with no human KPV clinical trial identified by the dated search. [2][6][3][7][4]
Questions
What kind of compound is KPV?
KPV is a tripeptide made of lysine, proline and valine, matching alpha-MSH residues 11-13. Its PubChem identifier is CID 125672. Peptides Collective lists the single-compound KPV product as a 10mg vial.
What does KPV stand for?
KPV names the sequence Lys-Pro-Val: lysine, proline and valine. It matches residues 11-13 at the C-terminal end of alpha-MSH. The verified record also uses Lys-Pro-Val and L-Lysyl-L-prolyl-L-valine as names for the same tripeptide.
Is KPV the full alpha-MSH hormone?
No: KPV matches the final three residues, positions 11-13, of alpha-melanocyte-stimulating hormone. The recorded name alpha-MSH (11-13) identifies that fragment. A research record about the full hormone should therefore be checked for whether it actually examines the KPV sequence.
Which PubChem record identifies Lys-Pro-Val?
PubChem CID 125672 is the verified record for Lys-Pro-Val, with CAS 67727-97-3. The verified compound check found that a name-only “KPV” lookup can resolve to an unrelated molecule. Search by the CID and compare the sequence as well as the name.
Are studies using human cells human clinical trials?
No: the KPV paper indexed as PMID 15102092 is labelled a cell study and examines signalling in human keratinocyte cells. Human cell origin describes the model's material; it does not establish research in human participants or a clinical result in people.
Has a human KPV clinical trial been identified?
No human KPV clinical trial was identified in the verified PubMed check dated 29 September 2026. Its search results included unrelated acronym matches, so a raw result count cannot be used as a count of trials involving the Lys-Pro-Val tripeptide.
Which research areas have KPV studies examined?
The key records cover signalling in human keratinocyte cells, PepT1-mediated uptake and intestinal inflammation in animal models, and a review of alpha-MSH-related peptides. These records support model-specific research conclusions; the dated search found no human KPV trial.
What adverse-event figures are available for KPV?
No attributable KPV adverse-event count or rate is available from the captured search summary. The fetched cell and rodent-colitis abstracts do not report adverse events, and no human KPV study was identified. Missing reporting cannot be converted into a finding that events never occurred.
Is KPV named on WADA's 2026 List?
KPV is not named on WADA's 2026 Prohibited List, according to the dated compound check. The check also records the S0 condition for non-approved pharmacological substances and leaves its application to KPV unconfirmed. Being absent by name is therefore insufficient to describe KPV as permitted in sport.
What is the price of KPV peptide?
The Peptides Collective catalogue lists the 10mg KPV vial from A$58. That is the product price, separate from courier charges. WA courier is A$15, with the courier charge waived for WA orders over A$150.
Can I request a certificate before choosing a KPV batch?
Yes: the certificate for a Peptides Collective batch is available on request using the compound, strength and batch number. Request the report for the batch you are assessing. The stated tests are purity by HPLC and identity by mass spectrometry.
Does HPLC purity confirm the amount of KPV in a vial?
HPLC purity and net peptide content are distinct measurements in the captured handling guidance. Net peptide content excludes counter-ions and water. Peptides Collective lists 10mg for its KPV vial, but that catalogue figure does not supply a measured batch-content result.
How is laboratory KPV concentration calculated?
Divide peptide mass in milligrams by solvent volume in millilitres. The captured example uses 10mg and 2 mL to give 5 mg/mL. Confirm the mass basis before calculating: HPLC purity does not replace net peptide content, and the example does not establish KPV solvent compatibility.
How long is a reconstituted KPV solution stable?
No KPV-specific measured shelf life is supplied in the captured handling guides. Their general guidance keeps working solutions at 2 to 8°C and distinguishes storage by solvent. A general opened-vial handling limit should not be read as proof of KPV chemical stability.
Sources
- 1. PubChem, National Library of Medicine
- 2. Dalmasso G et al. PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology, 2008.
- 3. Elliott RJ et al. alpha-Melanocyte-stimulating hormone, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cells. J Invest Dermatol, 2004.
- 4. PubMed, National Library of Medicine
- 5. Peptides Collective
- 6. Kannengiesser K et al. Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease. Inflamm Bowel Dis, 2008.
- 7. Brzoska T et al. Terminal signal: anti-inflammatory effects of α-melanocyte-stimulating hormone related peptides beyond the pharmacophore. Adv Exp Med Biol, 2010.
- 8. Peptides Collective
- 9. Peptides Collective
- 10. Peptides Collective
- 11. Federal Register of Legislation
- 12. World Anti-Doping Agency
- 13. Peptides Collective
