Peptides Collective research team.
Updated . How we research and review.
Short answer
5-Amino-1MQ is a small-molecule quinolinium cation studied as an NNMT inhibitor, with no amino-acid sequence or peptide length (CAS 685079-15-6; PubChem CID 950107). [1] Research covers cells and mice; a September 2026 search found no human clinical trials. [2] Our pick for laboratory sourcing is Peptides Collective's 5mg vial, with independent batch testing and a certificate on request. [3][4]
What identifies 5-Amino-1MQ, and what is in the vial?
5-Amino-1MQ's molecular identifiers describe the quinolinium cation, while the Peptides Collective vial is labelled 5mg. [1][4] Keeping the chemical identifier separate from the product specification matters because commercial salts can have a different formula and molar mass. [1]
| Identifier or specification | Verified detail |
|---|---|
| Chemical class | Small-molecule quinolinium cation studied as an NNMT inhibitor. [1] |
| Full name | 5-amino-1-methylquinolinium. [1] |
| Other names | 5-MQ; 5-Amino-1-methylquinolin-1-ium. [1] |
| Amino-acid sequence and length | Not applicable: the compound has no amino acids and is not a peptide. [1] |
| CAS | 685079-15-6. [1] |
| PubChem CID | 950107, the cation only. [1] |
| Cation formula | C10H11N2+. [1] |
| Cation molar mass | 159.21 g/mol. [1] |
| Peptides Collective vial contents | Labelled 5mg of 5-Amino-1MQ. [4] |
| Catalogue price | From A$68 for the 5mg vial. [4] |
The Peptides Collective 5-Amino-1MQ 5mg product page is the ordering destination for that strength. [4] The available product specification does not identify its counter-ion or confirm whether the labelled mass refers to the cation or a complete salt. [4] Check that mass basis in the batch documentation before converting milligrams to a molar concentration.
What has research examined?
5-Amino-1MQ research examines nicotinamide N-methyltransferase (NNMT) in cell and mouse models; the September 2026 PubMed search found no human clinical trials. [1][2] The studies address different questions, from cell proliferation to the microbiome and tumour biology. [5][6][7]
| Source | Stated model | What the study examined | What the evidence supports |
|---|---|---|---|
| 2021, PMID 33645410 | Cell: HeLa cells | Anti-proliferative activity of a small-molecule NNMT inhibitor | The study reported inhibition of HeLa cell growth, with the qualified observation that HEK-293 cell proliferation was not apparently affected. [5] This is in vitro evidence. [5] |
| 2022, PMID 35013352 | Animal: diet-induced obese mice | A reduced-calorie diet combined with NNMT inhibition and the microbiome | The paper concerns a distinct microbiome in that mouse model. [6] Its title and animal classification do not establish a human outcome. [6] |
| 2024, PMID 39067875 | Animal: tumour model | NNMT in cancer-associated fibroblasts, macrophages and resistance to immunotherapy in urothelial bladder cancer | The study is classified as animal research; no human clinical trial of 5-Amino-1MQ was found. [7] |
| PMID 29155147 | Animal: diet-induced obese mice; also cell work in cultured adipocytes | Methylquinolinium NNMT inhibitors, cellular metabolites and adipose biology | The abstract reported changes in intracellular NAD+ and SAM in adipocytes and changes in body weight, white adipose mass and adipocyte size in mice. [10] The abstract does not identify the specific analogue. [11] |
| Review | No review included in this study set | None captured | The sources cited here do not include a review of 5-Amino-1MQ. [2] |
| Human | No human clinical trial found in the dated search | None found | The dated search found no trial from which to state human outcomes or an adverse-event rate. [2] |
The related methylquinolinium paper measured the NNMT reaction product 1-methylnicotinamide (1-MNA) and metabolites including nicotinamide adenine dinucleotide (NAD+) and S-adenosylmethionine (SAM) in cultured cells. [10] Those measurements explain the laboratory interest in NNMT without establishing an effect in people.
Peptides Collective groups this compound in its metabolic research collection. [4] The tumour and cell-proliferation records show why its research literature is broader than a single metabolic question. [7][5]
What adverse observations have studies reported?
The related NNMT-inhibitor study, PMID 29155147, reported no observable adverse effects in diet-induced obese mice, but that observation is not a formal toxicology assessment. [11] The abstract refers to an inhibitor from a methylquinolinium series without naming the specific analogue. [11]
The study also reported no change in total food intake in those mice. [11] Its abstract-level observation should remain attached to that animal model and compound description. It makes no claim about people or every 5-Amino-1MQ preparation.
Cell-viability results from the same paper reported modest cytotoxicity for 5-amino-1MQ in 3T3-L1 pre-adipocytes at higher tested concentrations. [10] Cell cytotoxicity is a laboratory observation in cells only. [10]
The separate HeLa study's statement that HEK-293 proliferation was not apparently affected is also confined to cell culture. [5] The September 2026 adverse-event search found no human study or dedicated toxicology study of 5-Amino-1MQ. [2] Human adverse-event frequencies therefore cannot be reported from these sources. [2]
What is its Australian legal and WADA status?
5-Amino-1MQ is not named in the Poisons Standard (June 2026 instrument); the check completed on 29 September 2026 found no individual entry. [8] No named Appendix D entry is identified in that compound check. [8] A negative name search does not establish unrestricted supply or possession. [8]
The sport status checked on 29 September 2026 is: “Not named on the 2026 List. Class S0 (Non-approved substances) prohibits at all times any pharmacological substance not addressed elsewhere and with no current governmental approval for human therapeutic use; whether S0 applies was not confirmed here - check with Sport Integrity Australia.” [9]
Read the Australian peptide legal-status guide for the wider scheduling context. The dated name-search finding and the unresolved S0 applicability should both stay attached to any description of this compound's status.
How should 5-Amino-1MQ be handled for laboratory research?
Confirm the chemical form supplied before choosing a solvent or storage specification for 5-Amino-1MQ: it is a small molecule, and its commercial salt may differ from the cation listed in PubChem. [1] The available Peptides Collective specification does not confirm that salt form. [4]
For laboratory reconstitution, the reconstitution guide explains the general checks: match the batch, confirm the mass basis, measure the solvent volume and record the compound, solvent, concentration and date. [12] Concentration in mg/mL is the material's mass in milligrams divided by the solvent volume in millilitres. [12] Confirm the reported mass basis before using that calculation for a particular vial.
The storage guide covers sealed dry material, light and moisture protection, labelled solutions and temperature monitoring for peptides. [13] It does not supply a validated 5-Amino-1MQ solvent choice, storage temperature or stability period. [13] A peptide's amino-acid-based storage rule cannot serve as a stability specification for this small molecule. [1][13]
Request the Peptides Collective batch certificate and confirm the supplied material's handling details before planning the assay. We make the certificate available on request with the compound, strength and batch number. [3]
How does Peptides Collective supply 5-Amino-1MQ?
You can request batch evidence for Peptides Collective 5-Amino-1MQ and order with tracked dispatch from Perth: the 5mg vial is independently tested before sale, with a certificate on request. [3][4][14]
We test every batch through an independent third-party analytical laboratory for purity by HPLC and identity by mass spectrometry. [3] Read about the checks on our testing page. For batch documentation, start at our certificate of analysis page and request the certificate with the compound, strength and batch number. [3] Use the matching report to read the measurements for the batch you are ordering.
| Supply detail | Peptides Collective terms |
|---|---|
| Dispatch location | Perth, Western Australia. [14] |
| Dispatch cadence | Twice daily Monday to Friday and once on Saturday. [14] |
| WA courier | A$15 on the Australia Post network; free on WA orders over A$150. [14] |
| Outside WA | A$24 flat, tracked, with a signature required. [14] |
| Packing | Thermal insulation and plain outer packaging. [14] |
| Payment | PayID or bank transfer; the order ships once payment clears. [14] |
Check the shipping information when planning a laboratory order. Twice-daily weekday dispatch is the warehouse cadence; arrival depends on the courier. [14]
Bottom line
Choose the Peptides Collective 5-Amino-1MQ 5mg vial for a batch tested by an independent lab, a certificate on request and fast tracked dispatch from Perth. [3][4][14] We dispatch twice daily Monday to Friday and once on Saturday, with WA courier free over A$150. [14] Request the matching batch report and confirm the chemical form before planning laboratory handling.
Questions
Is 5-Amino-1MQ a peptide?
No. 5-Amino-1MQ is a small-molecule quinolinium cation with no amino-acid sequence or peptide length. Its placement in Peptides Collective's metabolic catalogue describes the research area. The chemical identity remains distinct from an amino-acid chain, which also matters when interpreting peptide handling guidance.
What does NNMT stand for?
NNMT stands for nicotinamide N-methyltransferase, the enzyme studied with 5-Amino-1MQ as an inhibitor. The cited papers examine NNMT in cell proliferation, mouse microbiome studies and tumour biology. Each finding belongs to its experimental model; the enzyme's name alone does not establish a human outcome.
Has 5-Amino-1MQ been studied in humans?
No human clinical trial was found in the PubMed search checked on 29 September 2026. The cited 5-Amino-1MQ records concern cell and animal models. This is a dated search finding, so it should not be rewritten as proof that no human study could ever exist.
What did the related mouse study report about adverse effects?
The abstract for PMID 29155147 reported no observable adverse effects or change in total food intake in diet-induced obese mice. It described a methylquinolinium NNMT inhibitor without naming the analogue. That observation is not a dedicated toxicology assessment or evidence of an adverse-event rate in humans.
Does PubChem CID 950107 identify the complete salt in a vial?
No. CID 950107 identifies the quinolinium cation; commercial material can be supplied as a salt with a different formula and mass. Peptides Collective's available specification does not confirm its counter-ion. Check the chemical form and mass basis before comparing a batch result with the cation's published molar mass.
How much 5-Amino-1MQ is in a Peptides Collective vial?
The catalogue lists a 5mg vial from A$68. That is the labelled product specification. A batch measurement is on the certificate, available on request. The available specification does not confirm whether the mass refers to the cation or a complete salt. Request the matching certificate before using the label mass in laboratory calculations.
How can I request the batch certificate?
Request it with the compound name, strength and batch number: for this product, 5-Amino-1MQ and 5mg plus the number on your vial. Peptides Collective makes the certificate available on request. Match the returned document to the batch you are checking.
What do HPLC and mass spectrometry test?
Peptides Collective uses HPLC to test purity and mass spectrometry to confirm identity, through an independent third-party analytical laboratory before sale. Request the certificate for the measurements that belong to your batch. Purity and identity checks do not establish a human outcome.
Does absence from the Poisons Standard settle its legal status?
No. The supported finding is that 5-Amino-1MQ was not named in the June 2026 Poisons Standard, with no individual entry found in the check dated 29 September 2026. That name-search result alone does not establish unrestricted possession or supply, and it should not become a blanket legal claim.
Does WADA's unnamed status mean it is permitted in sport?
No. WADA's S0 class can prohibit a pharmacological substance without naming it individually when its stated conditions apply. The check against the 2026 List did not confirm whether S0 applies to 5-Amino-1MQ and directs that question to Sport Integrity Australia. Absence by name is not a clearance.
Can I use a peptide storage guide as a 5-Amino-1MQ stability specification?
No. The house guides provide general peptide handling guidance. 5-Amino-1MQ has no validated stability specification in our records. This compound has no amino-acid sequence. Confirm the supplied salt, solvent compatibility and storage instructions for the material itself; the sources do not establish a refrigerated shelf life for this vial.
Where is it dispatched, and when is WA courier delivery free?
Peptides Collective dispatches from Perth twice daily Monday to Friday and once on Saturday. WA courier delivery is free on WA orders over A$150; outside WA the tracked flat rate is A$24 with a signature required. Dispatch follows cleared payment, so the warehouse cadence is separate from payment processing.
Sources
- 1. 5-Amino-1MQ chemical identity, parent-verified PubChem fields
- 2. Parent's dated PubMed study inventory and evidence-absence findings
- 3. Peptides Collective approved batch testing and certificate process
- 4. Peptides Collective approved 5-Amino-1MQ catalogue specification
- 5. Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cells
- 6. Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
- 7. NAD(+) metabolism enzyme NNMT in cancer-associated fibroblasts drives tumor progression and resistance to immunotherapy by modulating macrophages in urothelial bladder cancer
- 8. Poisons Standard June 2026: parent compound check
- 9. WADA 2026 Prohibited List: parent compound check
- 10. Captured full-text portion of the methylquinolinium NNMT-inhibitor study
- 11. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice
- 12. Peptides Collective general laboratory reconstitution guide
- 13. Peptides Collective general laboratory storage guide
- 14. Peptides Collective approved dispatch, delivery and payment terms
